Cisdiamminedichloroplatinum
Webcis-Diamminedichloroplatinum (II) induced distortion in a double-helical DNA fragment jeroen den hartog 1984, Journal of The American Chemical Society Download Free PDF Related Papers Journal of the … Mechanism of two-electron oxidation of deoxyguanosine 5'-monophosphate by a platinum (IV) complex 2004 • Amanda Hakemian Download Free … WebThree Co(III) complexes of a designed ligand PMAH that mimics the metal-binding domain of the antitumor antibiotic bleomycin (BLM) have been isolated and structurally characterized. The coordination
Cisdiamminedichloroplatinum
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WebJul 4, 1995 · The combination of cis-diamminedichloroplatinum(II) (CDDP) and 7-ethyl-10-[4-(I -piperidino)-I -piperidino]carbonyloxycamptothecin (CPT-I I), a topoisomerase-l inhibitor, has been shown to be synergistic in vitro and clinically active against several human cancers refractory to chemotherapy. To elucidate the mechanism of the … WebSpectrum of cis-diamminedichloroplatinum (II)-induced mutations in a shuttle vector propagated in human cells Spectrum of cis-diamminedichloroplatinum (II)-induced mutations in a shuttle vector propagated in human cells Authors G J Bubley 1 , B P Ashburner , B A Teicher Affiliation
WebAbstract Cis-diamminedichloroplatinum (DDP) was used as the initial treatment in a pilot study of 17 patients with biopsy-proven transitional cell carcinoma of the bladder. No … WebDec 3, 1979 · [Cis-diamminedichloroplatinum(II). A new antineoplastic agent derived from the group of heavy metal complexes (author's transl)] Platinum coordination complexes represent a new class of antineoplastic agents among which only cis-diamminedichloroplatinum(II) (cis-DDP) has undergone extensive clinical trials.
WebDec 1, 1992 · To elucidate the mechanism of the synergistic cytotoxicity of 5-fluorouracil (5-FU) and cis-diamminedichloroplatinum (II) (CDDP), we studied the interaction of these agents using a human squamous carcinoma cell line (HST-1). WebA total of 26 patients with biopsy proved epidermoid carcinoma of the penis (Jackson stage III or IV) with measurable disease, no prior chemotherapy and adequate renal function …
WebA docetaxel-resistant prostate cell line (PC3DR2) was subsequently established using the same method (9); resistance-associated genes in this cell line were examined in the present study through DNA microarray, western blot analysis and reverse transcription-quantitative polymerase chain reaction (RT-qPCR).
WebMar 1, 1979 · 1. Cisplatin is a co-ordination complex of a central platinum atom, two chlordies and two ammonia molecules in the “ cis ” position. 2. A prime mechanism of … portsmouth nh hampton inn downtownWebcis-Diamminedichloroplatinum(II): effects of a representative metal coordination complex on mammalian cells Pharmacol Ther. 1984;25(3):297-326.doi: 10.1016/0163-7258(84)90003-2. Author E B Douple PMID: 6542679 DOI: 10.1016/0163-7258(84)90003-2 No abstract available Publication types portsmouth nh guideWebJun 1, 1975 · Summary. The effects of cis -diamminedichloroplatinum (NSC 119875) on murine and human hemopoietic precursor cells were studied in culture. When murine … ora airbox s2WebAbstract Murine leukemia L1210 cells, either sensitive or resistant to the toxic action of the cancer chemotherapeutic agent cis-diamminedichloroplatinum (II), have been studied … ora acoustic pedalWebApr 19, 2024 · A platinum-based chemotherapeutic agent, Cisplatin (CDDP), has been widely used to treat many human cancer including cervical cancer, metastatic cancers and most of other solid tumors [1]. The cisplatin anticancer efficacy is owing to its interaction with chromosomal DNA. ora amar mukher kotha kaira nite chay lyricsWebNov 1, 1983 · cis -Platinum, bleomycin, 5-fluorouracil, and cyclophosphamide were administered to rodent and canine models of osmotic blood-brain barrier modification to evaluate the relationship between tissue drug concentration in brain and the physiological and neuropathological effects of the drug. ora as in energyWebcis-Diamminedichloroplatinum (II) - Trait. This product is a crystalline powder of bright yellow to orange yellow; Odorless. This product is soluble in dimethyl sulfoxide, slightly … ora and the wild wip