Cisplatin salt wasting

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August undefined, 2024

WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. During his five-day hospital course, his renal parameters steadily improved, and his serum sodium improved from 124 mEq ... WebDifferential diagnosis of hyponatremia induced by cisplatin-containing chemotherapy: syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt …

Cisplatin-induced hyponatremia in malignancy: comparison …

WebFeb 1, 2016 · Cisplatin may produce renal salt wasting causing symptomatic orthostatic hypotension and hyponatremia associated with abnormalities of the renin-aldosterone … WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting … greengate medical centre beverley

Cisplatin-induced renal salt wasting syndrome - PubMed

WebJan 25, 2012 · Hyponatremia associated with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt-wasting syndrome (RSWS) after platinum-based chemotherapy is not uncommon. However, no reports of RSWS following taxane monotherapy have been previously published. WebRenal salt wasting: urine Na will be high. Causes include salt-wasting nephropathy, adrenal insufficiency, cisplatin, and thiazide diuretic use. Euvolemic: Hypothyroidism: check TSH. Glucocorticoid deficiency: check AM cortisol. WebCisplatin induces both inflammation and vascular injury, which further promotes kidney injury. In addition to AKI, cisplatin causes proximal tubulopathy, salt wasting, loss of urinary concentrating ability, and magnesium wasting. View chapter Purchase book T cells in kidney injury and regeneration Li Li, ... greengate mechanical services

[Renal salt-wasting syndrome progressing to severe ... - PubMed

PROFOUND HYPONATREMIA AND DEHYDRATION: A CASE OF CISPLATIN INDUCED SALT …

WebCisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1 mg twice daily, oral salt tablets 1 g QID, sodium bicarbonate tablets … WebAug 1, 2024 · Cisplatin (CDDP) is an important anticancer drug. A common side effect of CDDP is renal salt and water-wasting syndrome (RSWS). The origin of RSWS is … greengate lighting control systemWebOct 6, 2016 · In the clinical setting, the most common and important manifestation of cisplatin nephrotoxicity is AKI, which can be progressive and even irreversible. Other renal manifestations include hypomagnesaemia, salt wasting, a … flu shot with lvn

"WebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, … " - Cisplatin salt wasting

Cisplatin salt wasting

Cisplatin - an overview ScienceDirect Topics

WebCisplatin is a well-known chemotherapeutic agent that can be associated with It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular... WebCisplatin Induced Renal Salt Wasting Syndrome: An Uncommon Diagnostic Distinction Session Information. Fluid, Electrolyte, and Acid-Base Disorders: Case Reports ... and recovery is the rule although recurrence is common. While carboplatin is less toxic, cisplatin has unequivocal superiority in most of the cancers in which it is used, making it ...

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WebMar 1, 2024 · Cisplatin may produce renal salt wasting causing symptomatic orthostatic hypotension and hyponatremia associated with abnormalities of the renin-aldosterone … WebCisplatin is known to induce Fanconi syndrome and renal salt wasting (RSW). RSW typically only requires transient normal saline (NS) support. We report a severe RSW case that required 12 liters of 3% saline. A 57-year-old woman with limited stage small cell cancer was admitted for cisplatin (80 mg/m 2) and etoposide (100 mg/m 2) therapy.

WebSalt wasting Cisplatin Azacitidine Syndrome of inappropriate antidiuresis Cyclophosphamide Vincristine Nephrogenic diabetes insipidus Cisplatin Ifosfamide Magnesium wasting Cetuximab, panitumumab Cisplatin Crystal nephropathy Methotrexate Acute interstitial nephritis Anti-CTLA-4 antibody WebSIADH, renal salt-wasting syndrome, and salt loss caused by vomiting and/or anorexia, should be diagnosed as accurately as possible in future studies. ... Alhosaini MN, Patel A. Cisplatin-induced renal salt wasting syndrome. South Med J. 2010;103(8):793–799. 5. Raftopoulos H. Diagnosis and management of hyponatremia in cancer patients.

WebRenal salt wasting syndrome has been described in 17 case reports since 1984. It is a rare side effect of cisplatin that manifests with polyuria, hypovolemia, and hyponatremia, … WebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical...

WebCisplatin-Induced Renal Salt Wasting Requiring over 12 Liters of 3% Saline Replacement Case Rep Nephrol. 2024;2024:8137078. doi: 10.1155/2024/8137078. Epub 2024 May 10. Authors Phuong-Chi Pham 1 , Pavani Reddy 1 , Shaker Qaqish 1 , Ashvin Kamath 1 , Johana Rodriguez 2 , David Bolos 2 , Martina Zalom 2 , Phuong-Thu Pham 3 …

WebWe diagnosed this clinical condition as renal salt-wasting syndrome (RSWS) on the basis of dehydration and high urinary sodium excretion at the onset. In the second course of chemotherapy, CDDP was replaced with carboplatin (CBDCA); consequently, hyponatremia was not observed. flu shot with shingles vaccineWebMay 19, 2024 · Rarely, cisplatin-related hyponatremia may result from Renal Salt Wasting Syndrome ( 33 ). Hypernatremia can also develop with cisplatin due to acquired nephrogenic diabetes insipidus with ensuing … greengate medical group beverleyWeb42%–100% of patients depending on total cisplatin dose and length of exposure. Hypomagnesemia and renal magnesium wasting may persist for up to 6 years after initial dose (5). Renal salt wasting syndrome has been reported in up to 10% of patients, manifesting as hyponatremia and severe ortho-static hypotension in the setting of high … flu shot workingWebNational Center for Biotechnology Information flu shot with whooping coughWebSep 1, 2002 · (6) The mechanism of cisplatin-induced hyponatremia is thought to be mainly renal salt wasting syndrome (RSWS), (7) (8) (9) (10) (11) (12) (13) and sometimes the syndrome of inappropriate... greengate medical guelphWebNov 1, 2003 · In 1988, Hutchison et al reported profound urinary sodium wasting in 7 of 70 patients treated with cisplatin over an 18- month period in 1 institution. 1 All the patients were men with carcinomas (including 1 patient with SCLC) and presented 2-4 months after starting cisplatin-based therapy with signs of vol- ume depletion, urinary salt wasting ... flu shot with symptomsWebDec 10, 2024 · A 20-year-old man developed renal salt wasting syndrome (RSWS) during treatment with cisplatin for germ cell testicular cancer. The man had non-seminomatous … greengate marie white